The Science Behind MI Paste™ and MI Paste Plus™

What is Recaldent™ (CPP-ACP)?

RECALDENT™ (CPP-ACP) contains Casein Phosphopeptides (CPP) and Amorphous Calcium Phosphate (ACP). Casein Phosphopeptides (CPP) are peptides derived from the milk protein casein that is complexed with calcium (Ca) and phosphate (PO4). In this complex, the CPP maintains/stabilizes the Ca and PO4 in an amorphous form (ACP) without precipitation.

How Does it Work?

RECALDENT™ (CPP-ACP) utilizes CPP peptides derived from the milk protein casein to maintain Ca and PO4 in an amorphous form (ACP). CPP will bind to surfaces such as plaque, bacteria, soft tissue, and dentin, providing a reservoir of bioavailable Ca and PO4 in the saliva and at the surface of the tooth. The Amorphous Calcium Phosphate (ACP) is released from the CPP complex during oral acidic challenges. Stabilization of ACP by CPP ensures the delivery of Ca and PO4 ions into tooth structure before they precipitate/ crystallize.

Frequently Asked Questions

How fast does MI Paste/MI Paste Plus work?

The speed of their effectiveness depends on each individual’s situation and specific clinical usage. For example, in a simple after-whitening procedure, relief should be possible within two minutes after application.

Can MI Paste/MI Paste Plus be used as a toothpaste substitute?

No. MI Paste/MI Paste Plus should be used in addition to regular brushing with toothpaste.

Is MI Paste/MI Paste Plus safe for people with lactose intolerance and milk allergies?

The active ingredient, RECALDENT™ (CPP-ACP), is a milk-derived protein and should not be used by anyone with milk protein allergies. MI Paste/MI Paste Plus has a lactose content of less than 0.01%.

Is MI Varnish gluten-free?

Yes, MI Varnish is gluten-free.

Are Fluoride Varnishes suitable for pre-school children?

Fluoride Varnish is the only in-office topical fluoride recommended for pre-school children.

Can MI Varnish be used on patients with crowns and veneers?

MI Varnish can be applied to the margin area of the crown or veneers.

Is prophylaxis (cleaning) required before the application of MI Varnish?

MI Varnish does not require a prophylaxis treatment before application.